http://wavefunction.fieldofscience.com/2010/11/why-are-secon...
Mentions here that secondary amines are usually the most basic, the latter property being needed for this reaction. Perhaps, indeed, not twice as
efficient, but a starting point nonetheless.
Quote: Originally posted by Nicodem | That is not the way the mechanism of this catalysis is generally considered. The primary amine is not just a base. It is also a catalyst. The
mechanism was already discussed on this forum, so UTFSE for details.
What you described is the mechanism of another reaction, the Henry reaction followed by elimination. |
OK, thanks; I appreciate the correction. Thanks for pointing that one out.
Overall, what would you answer to the OP's question, Nicodem?
[Edited on 22-8-2012 by Hexavalent] |