If you want hex-1-en-1-yl acetate, the simplest way I can imagine is to take hexanone, deprotonate, then react with acetyl chloride or acetic
anhydride. I have one it with TMSCl before and that works great. You may get some reaction of the ene, but you should be able to separate any, and
with the right base, I would think it would be minimized. |