Sciencemadness Discussion Board

CuI/L-Proline-Catalyzed Coupling Reactions of Aryl Halides with Activated Methylene Compounds

Sandmeyer - 28-1-2006 at 11:12

X. Xie, G. Cai, D. Ma, Org. Lett., 2005, 7, 4693-4695.

Abstract:

2-aryl-1,3-dicarbonyl compounds are produced in good yields by a CuI/L-proline-catalyzed arylation of activated methylene compounds with aryl iodides and aryl bromides in DMSO at 40-50°C in the presence of Cs2CO3.

http://rapidshare.de/files/12038468/ol0518838.pdf.html

Preparative info + proton-NMR spectra:

http://pubs.acs.org/subscribe/journals/orlef7/suppinfo/ol051...

From China with love.

[Edited on 28-1-2006 by Sandmeyer]