metaljack - 7-3-2006 at 01:26
，I produced the epoxide with (70%g/g) t-BuOOH or 35% H2O2 in the
dioxane,but the speed of reaction was slow(>80h),and the olefine remained 40%.
(E)-N,N-dimethylbut-2-enamide to N,N,3-trimethyloxirane-2-carboxamide.reacting at 30~35C,24%NaOH(aqus) as base.
1.I have tried to carry out this reaction in CH3OH,but more impurity appearing;
2.I runned the reaction with 10eq oxidant and 5eq base.
I don't kown why the reaction slowly,guess:the β－position
is not electron deficient.