Sciencemadness Discussion Board

Nitrile to ketone? with EtMgBr

stygian - 12-5-2006 at 15:19

What is/are the intermediates formed from methadone nitrile and EtMgBr, to eventually yield the ketone?

chochu3 - 12-5-2006 at 23:21

Are you asking for the mechanism or what is the product after 2,2-Diphenyl-3-methyl- 4-dimethylaminobutyronitrile reacts with the grignard reagent? After the grignard is reacted with the nitrile above it I believe is methadone at that point.

stygian - 13-5-2006 at 18:18

I was wondering about the intermediate

turd - 13-5-2006 at 23:03

A metalloimine R=NMgCl.
Come on, don't you have any OC-textbook or even google?