Hi I have been synthesizing P Benzo from Hydroquinone for a while now with a slightly modified version of an Erowid method involving H202 and Iodine
as a catalyst https://erowid.org/archive/rhodium/chemistry/benzoquinone.ht... but I recently stumbled on a method to make Benzoquinone from Acetaminophen using
DH2O and NaOH and it produces a very brown/black goo. Is there anyway the Benzo produced from Acetaminophen can be used in place of Hydroquinone?Nicodem - 2-4-2015 at 08:00
I this an April’s fools day question?Scr0t - 2-4-2015 at 10:39
Quote:
I recently stumbled on a method to make Benzoquinone from Acetaminophen using DH2O and NaOH and it produces a very brown/black goo.
Do you have a reference for this? What you describe just sounds like a base hydrolysis of paracetamol to p-aminophenol which would be very susceptible
to atmospheric oxidation under basic conditions to give the dark colour that you describe. Acid hydrolysis would be preferable.
As side note V2O5 catalyzed oxidation of hydroquinone with NaClO3 works well but gives very poor yields of
p-benzoquinone if applied to p-aminophenol.
I imagine you want p-benzoquinone for a Benzo-Wacker reaction given your previous post.
Aqua-regia oxidation of paracetamol is effective at making chlorinated benzoquinones although I don't know if they would be useful as an oxidant in
this reaction, maybe.
