Sciencemadness Discussion Board

trans-/esterification of ethylphenidate compound

slyder - 27-9-2015 at 06:40

Hi there !

I have been wondering if would be possible to convert ethylphenidate to methyl-phenidate group by simple esterification process. like :

dissolving ethylphenidate freebase in ether then adding Methanolic-H2SO4 10% and reflux it for about an 1hour ? Would be this sufficent task to converting it from ethyl to methyl group.

any proposal suggestions are kindly welcome :)

Thank You !

Best Regards
Slyder

[Edited on 27-9-2015 by slyder]