soma
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pH ~8 buffer
I'm looking for a buffer solution that would be suitable for eye drops at a pH of ~8.
Suggestions?
Thanks.
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Tsjerk
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Either phosphate or citrate.
https://www.google.nl/url?sa=t&source=web&rct=j&url=https://www.aaojournal.org/article/S1529-1839(04)70035-4/pdf&ved=2ahUKEwj6hNXWs-rd
AhWJaFAKHW53B1gQFjADegQIAhAB&usg=AOvVaw16v0xUSOd5qUJWgS30na0S
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fusso
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How come this is in radiochemistry?
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pantone159
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Some eye drops (e.g. 'Visine') use a borate buffer.
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soma
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I was trying to post in "biochemistry". But thanks for the replies.
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gdflp
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Thread Moved
3-10-2018 at 11:29 |
Metacelsus
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If you are making eye drops, be careful to ensure sterility. You wouldn't want to get any nasty eye infections.
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Tsjerk
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Sterilization through autoclaving is easy, if you don't have an autoclave (pressure cooker) you can also cook it au bain-marie.
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phlogiston
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Not your question, but make sure to match osmolality as well. OTC solutions for lenses contain a borate buffer. pH 8 is at the lower end of the range
in which borate has useful buffer capacity (pH 8-10)
Out of curiosity, why would you want to make eye drops yourself?
Because this was previously in radiochemistry, I thought you might be trying to prepare an atropine eye-drop solution, as people did in the early days
of research on radioactivity. They used to drop atropine solution in their eyes to widen their pupils, which allowed them to see alpha-particle
scintillations more readily.
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"If a rocket goes up, who cares where it comes down, that's not my concern said Wernher von Braun" - Tom Lehrer |
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