Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
 Pages:  1  ..  3    5
Author: Subject: help with mechanisms
myristicinaldehyde
Hazard to Others
***




Posts: 166
Registered: 23-4-2016
Location: .͐͌ ͛҉̻̫̰̻̖E̮ͮ̐́̚ ̢̗̅̉ͩ͂̒̌.̯̻̺̯̀̎͂̄ͩ̚
Member Is Offline

Mood: сорок пять

[*] posted on 2-3-2017 at 16:45


The simplest answer is that LAH is used strictly in anhydrous conditions, and reacts aggressively with any water that would form. Hydrolysis requires water. Ergo, LAH does not produce the hydrolyzed product.



If we don't study the mistakes of the future we're doomed to repeat them for the first time.
View user's profile View All Posts By User
sulfuric acid is the king
Hazard to Self
**




Posts: 94
Registered: 11-1-2017
Member Is Offline


[*] posted on 3-3-2017 at 17:55


What are differences of both methodes?I am still learning,i am interested in details...
View user's profile View All Posts By User
wg48
National Hazard
****




Posts: 821
Registered: 21-11-2015
Member Is Offline

Mood: No Mood

[*] posted on 26-11-2017 at 06:38


Below is a procedure for making an azobenzene that I am not familar with. Can anyone give me a name for the reaction or describe the mechanism.

Procedure, 4-nitrobenzoic acid (2.0 g, 12 mmol) and NaOH (5.75 g, 144 mmol) were mixed in 30 mL of water and heated until the solid dissolved. Glucose (13.0 g, 72 mmol) aqueous solution (20 mL) was added drop wise at 70C, initially yielding a yellow precipitate and subsequently a brown solution upon further addition of glucose. A stream of air was bubbled into the mixture overnight, resulting in a light brown precipitate, and then the precipitate was filtered. The cake was dissolved in 10 mL of water, and acetic acid was used to adjust the pH of the solution in the range of 5 to 6. Approximately 1.06g azobenzene-4,4 dicarboxylic acid as light pink powder was obtained by filtration, washed with 25 mL of distilled water, and dried to constant weight in an oven at 80C

aaexperiment.jpg - 9kB

I found this note Attachment: aaaaglurednitro.pdf (286kB)
This file has been downloaded 1100 times
View user's profile View All Posts By User
TGSpecialist1
Hazard to Self
**




Posts: 53
Registered: 24-12-2017
Member Is Offline

Mood: always tired

[*] posted on 5-3-2018 at 22:37


What is the mechanism of decarboxylation by molten NaOH/KOH?
For benzoate I think it's like in picture, but I'm not sure how it works for saturated carboxylate salts.

de.jpg - 20kB
View user's profile View All Posts By User
TGSpecialist1
Hazard to Self
**




Posts: 53
Registered: 24-12-2017
Member Is Offline

Mood: always tired

[*] posted on 5-3-2018 at 22:55


re:sulfuric acid is king
I'm sure that your nitroalkene can be directly be reduced to sec-butylamine with aluminium amalgam, since P2P + nitromethane + Al(Hg) reaction works to produce methamphetamine: https://erowid.org/archive/rhodium/chemistry/ritter-alhg.htm...
Nitroalkenes are prone to hydrolysis so the reaction has to be done in methanol or the product will be contaminated with 3-aminobutan-2-ol.
View user's profile View All Posts By User
JJay
International Hazard
*****




Posts: 3440
Registered: 15-10-2015
Member Is Offline


[*] posted on 2-9-2018 at 03:51


How do you use the Sandmeyer reaction to create a phenol in acidic solution?



View user's profile View All Posts By User
CharlieA
National Hazard
****




Posts: 646
Registered: 11-8-2015
Location: Missouri, USA
Member Is Offline

Mood: No Mood

[*] posted on 2-9-2018 at 16:10


My guess: starting with -NO2 or -NH2 prepare the diazonium salt with NaNO2/HCl and hydrolyze to the phenol.
My reference: Janice Smith, Organic Chemistry (2nd edn.), page 985.
View user's profile View All Posts By User
JJay
International Hazard
*****




Posts: 3440
Registered: 15-10-2015
Member Is Offline


[*] posted on 2-9-2018 at 16:28


The question is how to hydrolyze to a phenol in an acidic solution. Copper (I) hydroxide would be immediately destroyed, and while water is said to function to convert diazonium salts to hydroxides without copper catalysis, it's not clear how that works.

Edit: Apparently it works by just heating the diazonium salt in water. From what I gather, the reaction is SN1 with the rate determining step being the formation of the carbocation when the diazonium group leaves. I guess the carbocation attacks a water molecule and deprotonates it... then the proton meets up with the diazonium ion and generates acid and gaseous nitrogen?

So basically just crank up the temperature slowly until gas starts coming off and keep it at that temperature until the gas stops? (Oh and also probably don't do this in 60% sulfuric acid even though it's SN1, right?)



[Edited on 3-9-2018 by JJay]




View user's profile View All Posts By User
j_sum1
Administrator
Thread Untopped
1-12-2018 at 16:28
j_sum1
Administrator
Thread Topped
1-12-2018 at 16:29
MUSSUM
Harmless
*




Posts: 3
Registered: 24-4-2019
Member Is Offline


[*] posted on 28-4-2019 at 16:22


Hey man look at this book.
Pushing electrons, this book explain the electron flow, so very simple form, as simple as Kumon math course.

You make the download in this link:
https://b-ok.cc/book/2074519/c5f5b6
View user's profile View All Posts By User
chemrox
International Hazard
*****




Posts: 2961
Registered: 18-1-2007
Location: UTM
Member Is Offline

Mood: LaGrangian

[*] posted on 3-5-2022 at 15:57


"Many reactions are very well established by experimental methods. I don't know how familiar you are with labelling studies, kinetic isotope effects, ultrafast spectroscopy, etc."

Thank you!




"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
View user's profile View All Posts By User
Random
Temporarily Banned
*****




Posts: 1126
Registered: 7-5-2010
Location: In ur closet
Member Is Offline

Mood: Energetic

[*] posted on 5-10-2024 at 19:25


Mechanisms? Not a bad question.
View user's profile View All Posts By User
 Pages:  1  ..  3    5

  Go To Top