Huk40
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4-Methylpyridine
I want to synthesize that compound,but I can't seem to find any information on it's synthesis.I need it for the preparation of Brooker's merocyanine
(1-methyl-4-[(oxocyclohexadienylidene)ethylidene]-1,4-dihydropyridine, 'MOED') .Any ideas?
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ScienceSquirrel
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It is isolated from coal tar and made on an industrial scale and readily available so most chemists would not bother making it.
http://en.wikipedia.org/wiki/4-Methylpyridine
Look in the sweetie shop window!
http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en...
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Huk40
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I'm from Bulgaria,and here I can't find any firm that I could buy it from.
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ScienceSquirrel
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If you cannot buy 4-methylpyridine you will probably find it hard to buy the chemicals needed to make it.
The industrial synthesis from acetaldehyde and ammonia is easy and cheap to run but low yielding, requires serious gear and major purification of the
product.
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Aqua-regia
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Read this patent. If you have electric pipe-furnace and NH3 cylinder, than it is piece of cake.
http://www.wipo.int/pctdb/en/wo.jsp?WO=2005%2F063389&IA=...
[Edited on 29-3-2011 by Aqua-regia]
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ScienceSquirrel
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You might just be a little beyond the resources of the average shed chemist there! 
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Mindchemist
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I think 4-cresol and ammonia will work, though it would probably need a catalyst.
Wake up and smell the 2-furfuryl mercaptan.
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jon
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why 4 methyl?
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ScienceSquirrel
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Not a chance! 
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GreenD
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GOOD QUESTION.
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Mindchemist
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You could try 4-cyanopyridine and methyl iodide, though it would also release cyanogen iodide if the reaction would go as I expect. You could do the
reaction in a hydroxide solution to detoxify the cyanogen iodide to a iodide and isocyanic acid.
[Edited on 3-27-2011 by Mindchemist]
Wake up and smell the 2-furfuryl mercaptan.
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Mindchemist
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http://en.wikipedia.org/wiki/4-Picoline
Might be useful.
Wake up and smell the 2-furfuryl mercaptan.
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