TheChemINC
Hazard to Self

Posts: 61
Registered: 22-2-2012
Member Is Offline
Mood: fuming
|
|
Cleaning Chromatographic Silica Media
i just finished up puritying piperine from black pepper with my chromatography column. But i now have about 80g of "dirty" (which means that its still
white, but is probably covered in contaminates) silica media.
How should i go about cleaning this? just keep rinsing in a solvent like acetone? it seems like a waste... and expensive
thanks,
Alex
[Edited on 19-2-2013 by TheChemINC]
[Edited on 19-2-2013 by TheChemINC]
|
|
bananaman
Harmless
Posts: 19
Registered: 29-1-2013
Member Is Offline
Mood: No Mood
|
|
Since silica is considered to be a polar medium, why not try flushing the silica column with solvents that are more polar, e.g. MeOH or EtOH?
|
|
TheChemINC
Hazard to Self

Posts: 61
Registered: 22-2-2012
Member Is Offline
Mood: fuming
|
|
its not that i am having troulble separating all of the other crap from it, i just dont feel like spending alot of money on a gallon or two of acetone
to wash it....
|
|
fez
Harmless
Posts: 3
Registered: 27-1-2013
Member Is Offline
Mood: unsaturated
|
|
Quote: Originally posted by TheChemINC  |
How should i go about cleaning this? just keep rinsing in a solvent like acetone? it seems like a waste... and expensive
|
I've not done any chromatographic separations yet, but I've wondered about this issue too. Maybe a Soxhlet extractor would work, if you have one.
(PS - first post, but been lurking here for a few months on and off. Hi everyone!)
|
|