Sciencemadness Discussion Board

diethyl malonate drevatives

amrhamed2 - 2-3-2008 at 12:46

I want to know why on applying thoinyl chloride ...a mono substitution takes place ............is there any possibility to get disubstituted derivative

Is there any way to increase yield of such reaction


Second for adding hydrazine to diethyl malonate ...how to increase yield of such reaction

[Edited on 3-3-2008 by amrhamed2]

r.png - 12kB

Nicodem - 3-3-2008 at 07:57

Be more specific. I'm really not sure I understood what you are talking about. There is no reaction between diethyl malonate and thionyl chloride as far as I know. Are you perhaps asking about the chlorination of diethyl malonate with sulfuryl chloride?

amrhamed2 - 3-3-2008 at 09:21

sorry for ignorance....I attached an image in the main post ......what I mean is illustrated ...........

sparkgap - 4-3-2008 at 00:45

You might want to read this patent: http://www.patentstorm.us/patents/7208621-description.html

sparky (~_~)