Ormarion
Hazard to Self
Posts: 54
Registered: 19-12-2017
Location: France
Member Is Offline
Mood: Alkylating her DNA
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Caprolactam reduction to azepane?
Hey everyone, few weeks ago i recently made some cyclohexanone oxime im planning to turn into caprolactam following the many procedures online.
Even if its a nice molecule in itself i was actually wondering if it would be possible to reduce it to azepane
Of course my first idea would be to use LAH (wich is have), however i am not rly aware about the reactivity of the cyclic amide in itself, if it would
be reactive enough or even if it could open the cycle
I found a random wikipedia picture saying that NaBH4 and methane sulfonic acid could be used to but no references linked to it
I have access to most reagent that could be used to reduce it i believe so if anyone have ideas or acces to sites like scifinder i would gladly have a
look at your propositions. My final goal would be to make a video on it cause i mean, lets be honest 7 member rings are cool
Anyway thanks for anyone who take the time to answer this post !
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clearly_not_atara
International Hazard
Posts: 2701
Registered: 3-11-2013
Member Is Offline
Mood: Big
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Attachment: ViewFreeArticle(1).pdf (186kB)
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[Edited on 04-20-1969 by clearly_not_atara]
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