protection of one of the two ketone sites
Piperidione, 3,3-diethylpiperidine-2,4-dione, CAS 77-03-2, has two oxo groups. The molecule is almost bilaterally symmetrical, but not quite. One
of the two oxo's is adjacent to a piperidyl N. What I would like to do is perform reductive ams with different amines on both oxos or a reductive am
on one and maybe a Grignard to the other. Anyway, in order to be able to treat these separately it will be necessary to protect one of the oxos. I'm
asking if this is feasible and whether the placement of one of them adjacent to the secondary amine helps make this possible?
"When you let the dumbasses vote you end up with populism followed by autocracy and getting back is a bitch." Plato (sort of)
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