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Sauron
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Be very wary of diazomethane.
One of my friends in NJ has a couple of the Aldrich ClearSeal cased glassware kits for sale second hand.
I have not checked but I think these are 50-100 mmo0l scale and designed for Diazald
[Edited on 9-7-2009 by Sauron]
Sic gorgeamus a los subjectatus nunc.
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Polverone
Now celebrating 21 years of madness
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I agree that medicinal chemistry is fascinating and impressive. It is daunting how synthetically complex modern drugs can be. What's more impressive
yet is how cheaply they can ultimately be offered. If you look at the structure of something like omeprazole or loperamide it's surprising what can be
delivered for a few tens of cents per pill, retail.
PGP Key and corresponding e-mail address
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benzylchloride1
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The diazomethane will be prepared in very small quantites in a fume hood, wearing a respirator and with a threaded microscale distillation apparatus
on a very small scale. This is a substance that should be treated as a deadly poison and is not to be taken lightly. I am just curious about it use as
a methylation reagent and for increasing the length of a carboxylic acid by one carbon, the Arndt-Eistert reaction. I plan on using it to methylate
the hydroxyl group of vanillin on a 0.5g scale. 3,4-dimethoxybenzaldehyde is used in a number of complex natural product syntheses; but also is used
for some street drugs. Many useful and interesting chemicals for total synthesis have been banned because of their use in making drugs. I once tried
to go into a local GNC store to see if I could order some malic acid. The clerk asked me why I needed this, and I stated that I was going to conduct
some chemistry experiments. The clerk told me that chemistry experiments are illegal. I responded by telling him that I am not a drug cook and malic
acid is not a chemical that is used in drug synthesis as far as I know. The drug cooks have destroyed our hobby in the eyes of many people. I was once
accused of being a kewlish bomb maker when I bought some wink brand iron rust stain remover that contained sodium dithionate. It deeply troubles me
when people use this forum to directly discuss the synthesis of common street drugs. The information about these compounds and their production can be
easily located on the internet by a simple search. There is really no need to rehash what has been discussed time and time again on the hive. We have
become allowed the killer bees in and they are destroying our hobby. Still there is some useful information about some chemicals that can be found on
this site, but most of the procedures for intermediates such as methylamine HCl, allyl alcohol can be found in Vogels Practical Organic chemistry.
[Edited on 9-7-2009 by benzylchloride1]
[Edited on 9-7-2009 by benzylchloride1]
[Edited on 9-7-2009 by benzylchloride1]
Amateur NMR spectroscopist
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Sauron
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Polverone
I suppose you are being facetious.
I have done business with all the major chemical vendors in this Kingdon for a lot longer than this forum has existed.
The former deputy director of National Police is a close friend. When Asia Week submitted written questuibs ro the General for an interview, I wrote
his answers. Not translated. WROTE. They were published word for word. The General's men summarily executed 100 drug dealers in his career. That is
not the record. in a single 90 day period Prime Minister Thaksin, now a fugitive, has 2700 ALLEGED drug dealers killed. Most were just victims of
shakedowns by crooked cops and not into drugs at all. Thaksin was a crooked cop. The General is not, he was police escort for HM the King for 7 years
and comes from one of the richest families in Thailand who have served the monarchy for 3 centuries amd been rewarded with land. A LOT of land.
I spent 20 years working with thw Thai military at top level and still regularly lunch with thw former head of Military Intelligence and Special
Warfare Command. Same 20 years as a senior defense-intelligence journalist, bureau chief for the ten nation ASEAN grouping for a Washington bsdrf
publication. Accredited with US Embassy and Rhai Foreign Ministry.
Amd 9 years as international affairs director for a two term Thsi Drnator who was Dean of the Law School and son os a Supreme Court Justice,
Do you really think I need anything laminated from any Internet forum? You make me laugh, Polverone.
[Edited on 9-7-2009 by Sauron]
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Polverone
Now celebrating 21 years of madness
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Actually that post was for benzylchloride1 -- quote now edited in to make it clearer. And yes, the second half was facetious.
PGP Key and corresponding e-mail address
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Sauron
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OK. Suffice it to say that my professional life and my hobby ought not to be comfused.
As for the price of pills that is obviously a function of economy of scale. Big Pharma has that.
[Edited on 9-7-2009 by Sauron]
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turd
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Haha. Some people still have to learn about the inner workings of a drama queen. Though I wish the experience on no one.
Quote: Originally posted by benzylchloride1  | | Medicinal chemistry is a fascinating field. We need to have more discussion on synthesis of medicines that fix problems such as pennicillin instead of
a new way of making something like methamphetamine. |
No. Science need not have practical applications. c.f. amateur (from amare, to love).
| Quote: | | Ths synthesis of amphetamines has little to offer to the amateur beside a way of getting high or making a buck. |
Wrong. Amphetamine (derivate) synthesis is perfect for amateur chemists. Amphetamines are stable molecules, can be synthesized in a myriad of ways and
the precursors are easily acquired. There's some ingenuity involved in making amphetamines from scratch in a home setting, but it can be done. Perfect
for learning basic organic chemistry and at the same time doing some innovation without having access to a multi-thousand-dollar lab.
And please stop perpetuating that silly "quick money" prejudice. Most people doing amphetamine derivates do not sell. Batch sizes are typically in the
10g range and there's no market for those compounds. This is like claiming that all people interested in energetic materials are terrorists. Honi soit
qui mal y pense.
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Sauron
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It is the height of irresponsibility to post on this forum and exhort others to commit a felony.
In fact depending on where you are and where they are it may well be a felony in and of itself.
Do you seriously propose that there are no other compounds of equal or better pedagogical value amd other qualities that are legal?
RIDICULOUS.
[Edited on 9-7-2009 by Sauron]
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kclo4
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Sauron, What political party do you most agree with?
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crazyboy
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And Member of the Day is... Sauron with 18 posts! (soon to be 19 I assume) Why don't you stop this petty bickering and leave already?
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Sauron
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Because NOT doing do apparently pisses you off, of course. I just live to answer such idiotic questions from witless nonentities like you.
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Sauron
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In whuch country? I am a US citizem of USA not Thailand.
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kclo4
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Dang Mr. Sauron skipped over my question completely.. 
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a_bab
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Hmmm, this is really interesting.
I understand that there are some people here, who are fascinated by the explosives. Their goal is to synth as many as possible, and to test them is
grams amounts. Some would even make (interesting) videos. Once the "file" is completed, they go for the next target.
There are others into the lacrymators, vesicants, etc. I understand this, as being young I did all of these too. Nothing beats the sensation in the
lungs given by a whiff of chloropicrine.
Then, there are some obsessed by poinsons. Making cyanide is something they HAVE to do, although they won't obviously test it, more then feeling the
stinging bitter smell. Some would even atempt ricin extraction. Why on Earth? Well, just for the sake of it: "I've done it."
Usually all the big chemists have been atracted in this field by these "naughty" reactions.
But being one who had never been high with a single exception (during a surgery - N2O), I just can't uderstand these meth cooks. I mean, if I'd be for
making meth, but not sell it, I'm certain that I'd either consume it myself, or I'd be a consumer of dopes anyway, since I'd be atracted to this side
of chemistry.
Either case, something to puke on.
Explosives/poisons are much less of a problem to the forum then dopes. It's all about the dopes, since someone willing to blow up something won't
learn how to on a forum anyway.
It's a personal preference, but I'd just delete all the threads involving dopes all in all. I mean, "easy ketamine"? WTF is that?
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kclo4
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Ah tricky tricky... post the same time I do.. 
The USA would be good.
I've noticed you have been being pretty lazy with spelling lately, something up with that? It just doesn't seem like you is all.
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Sauron
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kclo4
No I didn't. You asked what po;l party O most agree with. I asked in which country? I'm an American expat ;living 20 years in Thailand.
I suppose you know nothing of Thai politics and you probab do not mean Ewanda.
In USA I would bring back the Bull Moose Party as Teddy R was a hard act to follow
Typos not spelling. A combination of an overdate intraocular implant (IOL) and diabetic retinupathy. I am going blind abd having trouble seeing the
keyboard well.
[Edited on 9-7-2009 by Sauron]
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kclo4
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Interesting, what do you think of the libertarian political party?
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Sauron
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Political discussions are prohibited I believe.
[Edited on 9-7-2009 by Sauron]
[Edited on 9-7-2009 by Sauron]
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kclo4
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Well, do you mostly agree or mostly disagree with the group?
Why do you agree/disagree about certain aspects of the libertarian party? And why?
[Edited on 9-7-2009 by kclo4]
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Sauron
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| Quote: Originally posted by kclo4 | Well, do you mostly agree or mostly disagree with the group?
Why do you agree/disagree about certain aspects of the libertarian party? And why?
[Edited on 9-7-2009 by kclo4] |
Political discussions are prohibited. It's a policy of polverone that I agree with.
[Edited on 9-7-2009 by Sauron]
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kclo4
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prohivired?
How is that any difference then talking about the ethics, consequences etc of drug cookery and how it relates to amateur chemistry?
Isn't it really all just politics and opinions that hardly relate to chemistry? Not that this thread was ever meant to relate to chemistry.
Libertarians I think would allow for a lot of amateur chemistry since they are for both economic and social freedom.
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Eclectic
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Sauron, would you please just come back inside and close the door? It's Summer, and you are letting out all the airconditioning. 
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Sauron
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| Quote: Originally posted by kclo4 | prohivired?
How is that any difference then talking about the ethics, consequences etc of drug cookery and how it relates to amateur chemistry?
Isn't it really all just politics and opinions that hardly relate to chemistry? Not that this thread was ever meant to relate to chemistry.
Libertarians I think would allow for a lot of amateur chemistry since they are for both economic and social freedom. |
I do not regard being anti-drug as political. I regard Nicodem's arhument to contrary is a bogus manipulation in order to apply the political ban in
order to silence me on drugs, see?
[Edited on 9-7-2009 by Sauron]
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kclo4
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Did I ever say it was electable, or even hint at it?
I was asking your opinion on it, that is really all I did.. Haha you are a nasty little bugger aren't ya?
Edit: This may not be a bad thread to boycott...
[Edited on 9-7-2009 by kclo4]
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Sauron
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Eclectic
Sorry. No.
Itls always summer in Bangkok and my room is the only one in the great big house without aircon. I an acclimatized.
I will not return to the tyranny of Nicodem.
[Edited on 9-7-2009 by Sauron]
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