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aliced25
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[*] posted on 16-11-2011 at 02:02


Be a bloody sight smaller soon with luck:cool:

Anyone interested in a prototype modified halbach array that will be being tested with a simplified spectrometer? The design is going to be being optimized for use at around 50-51MHz and will use opensource software (at the moment)... It is potentially a one-off chance to get involved in something that involves some absolutely "mad science" at home, is fairly cutting edge and a boon to amateur/beginner scientists.

The array is Patent Pending (otherwise the Company involved would potentially/probably have to pay a fucking license fee to build their own design). I've spoken with the parties involved and their aim is to get a 50-51MHz machine, using thick walled 4-5mm tubes (of lower than standard length - but fairly standard all the same), that has similar performance characteristics to the PicoSpin (in terms of size, ease of use & output), to the market at ~$1,000US within 12 months (obviously they are aiming for maximum market disruption). Similar advances in ease of use, size and accessibility in conjunction with low-cost compared to high-end markets, have been successful before (http://mitpress.mit.edu/books/NORVH/chapter2.html):P

[Edited on 16-11-2011 by aliced25]




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Polverone
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[*] posted on 20-9-2013 at 00:04
A wealth of desktop NMR machines: comparisons?


A lot has changed since the picoSpin 45 was launched in 2010. The company was acquired by Thermo Scientific. They now offer a higher resolution model, the picoSpin 80, at 19 kg mass instead of 4.8 kg for the original. It still uses small capillary tubes.

There's a <a href="https://en.wikipedia.org/wiki/Benchtop_NMR_spectrometer">list on Wikipedia</a> of benchtop NMR spectrometers, all based on rare earth permanent magnets as far as I can tell. Some use small capillaries to hold samples while others use standard NMR tubes. For some you'll need a sturdier bench: 170 kg or more.

The Wikipedia page is somewhat out of date. It lists:
The <a href="http://www.magritek.com/products-spinsolve">Magritek Spinsolve</a>, 42.5 MHz.
The <a href="http://www.picospin.com/products/picospin-45/">Thermo Scientific picoSpin 45</a>, 45 MHz.
The <a href="http://www.nanalysis.com/nmready60p.html">nanalysis NMReady</a>, 60 MHz.
The <a href="http://www.oxford-instruments.com/businesses/industrial-products/industrial-analysis/campaigns/something-is-missing/pulsar-delivering-nmr-to-you r-benchtop">Oxford Instruments Pulsar</a>, 60 MHz.

It is missing:
The <a href="http://www.picospin.com/products/picospin-80/">Thermo Scientific picoSpin 80</a>, 80 MHz.
The <a href="http://www.bruker.com/products/mr/compact-mr/fourier-60/overview.html">Bruker Fourier 60</a>, 60 MHz.

Apart from price, what are strengths and weaknesses of these various systems? Anyone well versed in NMR care to offer an opinion? For example, there are three nominally 60 MHz instruments available -- what else is important in choosing between them?

Edit: some <a href="http://process-nmr.com/WordPress/?p=273">external commentary</a>.

[Edited on 9-20-2013 by Polverone]




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[*] posted on 20-9-2013 at 03:45


Quote: Originally posted by Polverone  
The Wikipedia page is somewhat out of date.
I'll see what I can do.

Interesting find, <strong>Polverone</strong>. Thanks for this update. :)

[edit] Sloppily added the new spectrometers to the Wikipedia page. Are you considering purchasing one of these, or are you just curious?

[Edited on 20.9.13 by bfesser]




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[*] posted on 20-9-2013 at 07:45


There is an older discussion of tabletop NMRs on the technology section of the forum, a bit old now.

http://www.sciencemadness.org/talk/forumdisplay.php?fid=9

and go back a few pages. or just search NMR there.

But I am very amazed at what can be done now, I remember when T60's were considered great machines, and then new 90 Mhz machines came along and even had floppy disk drives. Thanks to Picospin for starting to make it better and smaller.

Once someone makes a 45 MHz machine, then people will figure out how to improve it, that is the great part. Eventually we might have much better small systems, but incremental change is sometimes part of the systems, so every little bit of improvement is great.
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[*] posted on 20-9-2013 at 08:18


I am just interested in the capabilities of the machines. The picoSpin 45 was around $20,000 when announced, which made it a cost breakthrough but still out of my price range. I am guessing that the newer machines are at least as expensive. Some day I'd like to have something from this class of machines, but I will have to wait until the second hand market is more developed or until there is more price competition among new models.



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[*] posted on 20-9-2013 at 09:09


I'm waiting until they incorporate a miniscule GC-MS/NMR/HPLC/UV-Vis./FT-IR/STM/XRD/bag of chips on a chip into a cellular telephone. :P

Oh, and better throw in some lasers, as well&mdash;just in case. Who knows, maybe some day in the distant future you'll even be able to use a cellular telephone to make an actual phone call&mdash;one where you can understand eachother!




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[*] posted on 9-4-2016 at 07:13


Found this page comparing different benchtop NMRs
http://www.cbrnetechindex.com/Chemical-Detection/Technology-...

Prices range from $13 for SpinnSolve (Magritek), $30k for the picoSpin (ThermoFisher) to $65k for the Pulsar (Oxford Instruments).

[Edited on 9-4-2016 by pdm55]
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