Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
Author: Subject: Synthesis of N,N'-dialkyloxamides
Bedlasky
International Hazard
*****




Posts: 862
Registered: 15-4-2019
Location: Beleriand
Member Is Offline


[*] posted on 10-1-2021 at 11:25
Synthesis of N,N'-dialkyloxamides


I successfully prepared N,N'-dicyclohexyloxamide, N,N'-dicyclopentyloxamide and N,N'-dibenzyloxamide from corresponding amines and diethyl oxalate. Synthesis is quite easy and you can do it just with basic lab equipment in high yields. Reaction doesn't proceed with sterically hindered amines, such as tert-butylamine. Aromatic amines like aniline also doesn't give a reaction. I tried both these amines without result.

Write up is on my website in czech/english




If you are interested in aqueous inorganic chemistry look at https://colourchem.wordpress.com/main-page/

I can offer GC analysis of samples. Just U2U to me for more info.

"An old friend once told me something that gave me great comfort. Something he had read. He said that Mozart, Beethoven and Chopin never died. They simply became music." Dr. Robert Ford, Westworld
View user's profile Visit user's homepage View All Posts By User
vano
National Hazard
****




Posts: 495
Registered: 22-3-2019
Location: Georgia, Kutaisi
Member Is Offline


[*] posted on 10-1-2021 at 13:01


Good work Bedlasky. Are you going to store these compounds if you use them in a future project?
View user's profile View All Posts By User
Bedlasky
International Hazard
*****




Posts: 862
Registered: 15-4-2019
Location: Beleriand
Member Is Offline


[*] posted on 10-1-2021 at 15:58


Thanks. I don't have use for them, I just wanted to try this reaction.



If you are interested in aqueous inorganic chemistry look at https://colourchem.wordpress.com/main-page/

I can offer GC analysis of samples. Just U2U to me for more info.

"An old friend once told me something that gave me great comfort. Something he had read. He said that Mozart, Beethoven and Chopin never died. They simply became music." Dr. Robert Ford, Westworld
View user's profile Visit user's homepage View All Posts By User
njl
International Hazard
*****




Posts: 582
Registered: 26-11-2019
Location: under the sycamore tree
Member Is Offline

Mood: ambivalent

[*] posted on 11-1-2021 at 09:40


Relevant paper: https://doi.org/10.1016/j.cclet.2018.01.003
And abstract: https://www.sciencedirect.com/science/article/abs/pii/S10018...
View user's profile View All Posts By User
Pumukli
International Hazard
*****




Posts: 615
Registered: 2-3-2014
Location: EU
Member Is Offline

Mood: No Mood

[*] posted on 12-1-2021 at 05:16


Congrats for the preparations!

Actually they are the first reported successful "ester aminolysis" reactions on SM as far as I know. :-)
View user's profile View All Posts By User

  Go To Top