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Author: Subject: Hydrogen peroxide penetrability
kin
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[*] posted on 26-3-2005 at 06:54
Hydrogen peroxide penetrability


I am looking for a way to make 3% H2O2 absorbable from skin in to blood steam for a skin treatment method.

Could it be possible to use it with some kind of zelatinous mass, to prevent hydrogen peroxide from vapourising and at the same time be friendly to the skin?
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BromicAcid
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[*] posted on 26-3-2005 at 08:57


I always figured H2O2 would be a bad thing to have go straight into the bloodstream. There is always DMSO, that seems to be one of the first things you try to accomplish putting something through the skin into the blood stream. However such solutions may have to be made up only minutes before usage elsewise there may be odd products between the reaction between the DMSO and the hydrogen peroxide, although not much considering the dillution of the peroxide.

Any kind of cream or 'gelatenous' mass that you incorporate H2O2 into is going to slow its rate of volitization. But peroxide is fairly reacitve so finding a suitable medium to incorporate it into may take some doing.

[Edited on 3/26/2005 by BromicAcid]




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kin
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[*] posted on 26-3-2005 at 09:41


Could 3% H2O2 penetrate skin in to blood by itself?
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Saerynide
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[*] posted on 26-3-2005 at 10:08


Just curious, why do you want H2O2 in your blood? :o Our bodies try to get rid of H2O2...

You're not trying to kill anyone/thing, by making oxygen bubbles form in their bloodstream, are you? :o




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[*] posted on 26-3-2005 at 10:32


You should know that smal concentrations H2O2 is administred intravenusly in patients and guess what! They don't die!
Our bodies (cells) MAKE H2O2 to fight infection. Ever heard of catalase enzyme?

Now can someone answer if 3% H2O2 can penetrate skin in blood steam?
I just need a way to add extra oxygen in blood without making a hole on skin or taking oraly.

[Edited on 26-3-2005 by kin]

[Edited on 26-3-2005 by kin]
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neutrino
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[*] posted on 26-3-2005 at 10:51


Why do you want to add oxygen to the blood? Whatever the reason, hydrogen peroxide is definitely not the best way to do it. H<sub>2</sub>O<sub>2</sub> has the peroxide ion(?) in it, making it very dangerous to anything living. When applied to the skin, it kills bacteria but doesn’t penetrate the epidermis (which is comprised of dead cells, essentially plates of keratin). Drinking the stuff or, worse yet, taking it intravenously would be a very bad idea. The entire purpose of the enzyme catalase is to protect the body by destroying hydrogen peroxide. Furthermore, anything but very concentrated hydrogen peroxide could only release a tiny amount of oxygen. For example, a 3% solution can release 10 times its volume of oxygen. If you really want more oxygen in your blood, get an oxygen tank and add that to your air supply.
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[*] posted on 26-3-2005 at 11:02


When adding H2O2 on a open wound doesn't some gets in to blood?

You said that H2O2 does not penetrate the skin keratin but when decomposed the free O radicals should penetrate it, am i right?

[Edited on 26-3-2005 by kin]
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[*] posted on 26-3-2005 at 11:04


Some gets into the blood, not much. As for H2O2 going through the skin, our skin is somewhat hydrophobic. As such it won't let much H2O2 through at all.



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kin
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[*] posted on 26-3-2005 at 11:09


I need mostly to add oxygen vascularly under a specific area of the skin. But i am not sure if it will moving around the specific area or disolve on all cardiovascular system.
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[*] posted on 26-3-2005 at 20:25


Yes, I have heard of catalase. It breaks down H2O2 into H2O and O2... that's where I got my idea from....

Because I got the impression that you didnt want it to break down until it got into the bloodstream, the first thing that came to mind was catalase in blood + H2O2 = O2 bubbles

[Edited on 28-3-2005 by Saerynide]




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[*] posted on 27-3-2005 at 01:21


I just need a minor increase in oxygen or H2O2 ijn blood not anything lethal.
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vulture
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[*] posted on 27-3-2005 at 01:51


Take a needle, sting yourself and add a drop of blood to your 3% H2O2 and observe. Now imagine that happening in a rather important artery.

Right, that's a full blown stroke you have there! :o




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[*] posted on 27-3-2005 at 02:01


Quote:
Originally posted by kin
You should know that smal concentrations H2O2 is administred intravenusly in patients and guess what! They don't die!


Actually, they often do...

http://www.myrtlebeachonline.com/mld/myrtlebeachonline/news/...

Quote:
Our bodies (cells) MAKE H2O2 to fight infection. Ever heard of catalase enzyme?


Wrong again. Cells make small quantities of hydrogen peroxide as an unwanted (and toxic) byproduct of metabolism. Catalase's role is to break it down, not to make it.

Quote:
When adding H2O2 on a open wound doesn't some gets in to blood?


When applied to an open wound, hydrogen peroxide will rapidly decompose into oxygen and water (hence the foaming). In this case, no harm is done, as the oxygen can easily escape. If hydrogen peroxide enters a closed blood vessel, there is no route of escape, and so dangerous oxygen bubbles will form.

Quote:
I need mostly to add oxygen vascularly under a specific area of the skin. But i am not sure if it will moving around the specific area or disolve on all cardiovascular system.


Oddly enough, it will move around. That is the basic idea of the cardiovascular system.


Oxygen therapy is dangerous quackery.

http://www.quackwatch.org/01QuackeryRelatedTopics/Cancer/oxy...

Given your manfest lack of scientific knowledge, I'd strongly advise you against attempting any medical procedure.

[Edited on 27-3-2005 by I am a fish]




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kin
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[*] posted on 27-3-2005 at 02:02


This is why i need epidermic use.

When aplying h2o2 on the skin the oxigen ingreases in outer cells, slowly the released oxygen absorbed from skin (not pure h2o2)

could this be possible?
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[*] posted on 27-3-2005 at 06:19


Please make your posts a little more clear. I don't quite understand the point of that last one.

I'd advise actually reading that last article, it thoroughly debunks the myths you are plagued with.
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[*] posted on 27-3-2005 at 08:21


Apparently, I have been beaten to the explanation regarding the antimicrobial mechanism and toxicity of peroxide ion, so I'll just throw in my two dimes worth. :D

"Epidermic" use, you say? Maybe you meant "external" use. I have yet to hear of this adjective!!!! Yes, the byproduct of peroxide decomposition is oxygen. But not your garden-variety oxygen, but nascent oxygen!!! That's right, kiddies, not the kind of oxygen you'd want in your bloodstream!!!!! And since catalase occurs in skin tissue, the nascent oxygen thus produced kills the bacteria on the surface of your recent trauma, and the bubbling action helps loosen detritus besides.

BUT, the nascent oxygen thus produced IS NOT, I repeat, IS NOT ABSORBED by the skin, and if ever some do, catalase sics 'em. ;) Thus, using peroxide to deliver oxygen inside you is definitely something to cross out of your to do list. Why the interest anyway??

sparky (^_^)

P.S. If you don't know what nascent oxygen is, search for it. Google helps. :D

[Edited on 28-3-2005 by sparkgap]




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[*] posted on 27-3-2005 at 14:40


Add my bit.
If you can selectively target an area of the human body with an over dose of O2 then you have cracked it. How you get it through the blood to where you want is the problem.
mick
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[*] posted on 28-3-2005 at 04:15


Forgive me if my syntax is terrible but my english is not that good.

In simple words i want to use H2O2 for its oxygen and not actualy the material itself.

I know that skin uses the atmosperic oxygen, nascent as you say. In hyperbaric oxygenetion therapies the pressure helps oxigen get in to blood steem trough skin.
What i need is to use a method (safe) to do the same thing using oxigen from H2O2. Of course in a smal scale and at a specific area.

I am not trying to sound smart or try to do any harm i just try to find an experimental way to use hydrogen peroxide on internal injury treatments.

thanks for your inputs until now and for all those to come.

[Edited on 28-3-2005 by kin]
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[*] posted on 28-3-2005 at 09:05
Oxygen


More oxygen in the blood ? Wouldn't it be easier to get an oxygen cylinder or generator ?
Before she passed away from emphysema and strokes my mother was using both.




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[*] posted on 28-3-2005 at 10:42


So this is the only safe way to put more oxygen in blood?

The oxygen released from H2O2 decomposition for example MnO2 + H2O2 could be breathable?
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[*] posted on 28-3-2005 at 11:02


I would have thought that by bubbling oxygen from the decomposition through some Drechsel bottles with water you could clean it up fairly well - theres only peroxide vapour to be worried about really.

Personally speaking I wouldn't really want to consume anything I make that could theoretically be consumed safely, just in case - but I suppose oxygen generated in the decomposition can't be all that more hazardous than the odd whiff of acetone or DCM one gets from time to time.

Can it?

Still, it's your call.
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[*] posted on 28-3-2005 at 11:30


How exactly the decomposition could increase the oxygen in blood? Just use Mno2 + H2O2 filtered through water and take deep breaths?

Any simple aparatus needed?

[Edited on 28-3-2005 by kin]
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[*] posted on 28-3-2005 at 11:32


Kin
I am not sure what you are talking about.
To get more oxygen into the body use H2O2 to increase the percentage of O2 in air from 20% to 23-25% or some thing and make sure your O2 is not contaminated. If you are treating a local injury I do not think you should fill the whole body with O2.
mick

Above that things might start catching fire

[Edited on 28-3-2005 by mick]
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[*] posted on 28-3-2005 at 11:36


I can't find any other way to increase "topical" the oxygen than filing with a little extra oxygen the hole body.

With what could oxygen be contaminated when using the proccedure with the decomposition?

[Edited on 28-3-2005 by kin]
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[*] posted on 28-3-2005 at 11:55


Then do not do it
mick
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