parabola
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Alternatives to Hofmann rearrangement
Can anyone suggest another reaction which also rearranges an aromatic primary amide to a primary amine with one less carbon atom?
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solo
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......make the carbamate then hydrolyse to the desired amine....solo/java
It's better to die on your feet, than live on your knees....Emiliano Zapata.
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Nicodem
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Thread Split
6-6-2016 at 12:33 |
Nicodem
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Thread Moved
6-6-2016 at 12:35 |
Nicodem
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I removed all the posts related to nonsensical insinuations on account of parabola's intentions. Please restrain on accusing new members of being drug
cooks when the question shows nothing of this kind.
Alternatives to Hoffman rearrangements are all the related rearrangements:
Curtius rearrangement
Lossen rearrangement
Schmidt rearrangement
…there is a human touch of the cultist “believer” in every theorist that he must struggle against as being
unworthy of the scientist. Some of the greatest men of science have publicly repudiated a theory which earlier they hotly defended. In this lies their
scientific temper, not in the scientific defense of the theory. - Weston La Barre (Ghost Dance, 1972)
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