Sciencemadness Discussion Board
Not logged in [Login - Register]
Go To Bottom

Printable Version  
Author: Subject: Methylating an amine

Posts: 5
Registered: 3-11-2016
Member Is Offline

[*] posted on 3-11-2016 at 12:10
Methylating an amine

Hi, does anyone know how I'd perform the following reaction? Thanks ^.^

[Edited on 3-11-2016 by flyingbutthole]

path4179.png - 7kB
View user's profile View All Posts By User
Hazard to Others

Posts: 168
Registered: 28-6-2016
Location: CA
Member Is Offline

[*] posted on 3-11-2016 at 12:46

Are you trying to make amphetamine?

That reaction is not easy. The only idea which comes to mind is oxidation of your amine (phenethylamine) to the nitrile (benzyl cyanide), alkylation with methylmagnesium iodide to the ketone (phenylacetone), followed by reductive amination to the desired product.
View user's profile View All Posts By User
Super Moderator
Thread Moved
3-11-2016 at 12:56
Super Moderator

Posts: 2502
Registered: 11-1-2014
Location: Austin, TX
Member Is Offline

Mood: Phenolic

[*] posted on 3-11-2016 at 12:57

Cookery related spoonfeeding

Come check out the Official Sciencemadness Wiki
Have a particular topic you're really interested in currently? Why not make a page for it? The wiki can always benefit from more contributors.

My (now defunct) YouTube Channel: Texium
My blog: Texium
View user's profile Visit user's homepage View All Posts By User

  Go To Top