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Author: Subject: Methylating an amine
flyingbutthole
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[*] posted on 3-11-2016 at 12:10
Methylating an amine


Hi, does anyone know how I'd perform the following reaction? Thanks ^.^





[Edited on 3-11-2016 by flyingbutthole]

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Cryolite.
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[*] posted on 3-11-2016 at 12:46


Are you trying to make amphetamine?

That reaction is not easy. The only idea which comes to mind is oxidation of your amine (phenethylamine) to the nitrile (benzyl cyanide), alkylation with methylmagnesium iodide to the ketone (phenylacetone), followed by reductive amination to the desired product.
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[*] posted on 3-11-2016 at 12:57


Cookery related spoonfeeding



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