Heat to complex?
I am now working on the tranditional Baylis-Hillman reaction. most of the papers on this topic performed this reaction at room temperature, 0 degree
or even more lower. however, few articles are reported at high temperature. it was said that when heating the mixture, though finished in a short
time, the yield and the selectivity dropped considerably. so why could this happen, and do there exist some others methods besides at high pressure?
thanks so much for reply.
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