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Drug Database Link
This is my own personal collection of homebrew efforts i have made into drug discovery since graduat ...
13-2-2022 at 03:35
by: Illegal Parkinson
Drug Database Link
This is a big database. Considering I obtained my masters in 2004, that's 18 years of post graduate ...
12-2-2022 at 01:17
by: Illegal Parkinson
Drug Database Link
Here is an alternate place to store it:

https://www.mediafire.com/file/dgc2uy3jlfyj5er/Drug+Datab ...
11-2-2022 at 01:40
by: Illegal Parkinson
Drug Database Link
Are you able to access it?

The file search does not seem to work as well as on onecloud.

Mega ...
9-2-2022 at 23:49
by: Illegal Parkinson
Drug Database Link
I made a drug database available to view.

https://aspera.pub/Wxi-c-U

This is the Feb 2022 edit ...
9-2-2022 at 12:55
by: Illegal Parkinson
Dibenzo[b,f]oxepin-10(11H)-one [5024-70-4]
I got a whole army of RMI # codenumbers from pubchem if someone can help me.

Potentially, Thiosal ...
9-2-2022 at 07:19
by: Illegal Parkinson
Dibenzo[b,f]oxepin-10(11H)-one [5024-70-4]
Here is the reaction i am interested in:
8-2-2022 at 06:43
by: Illegal Parkinson
Dibenzo[b,f]oxepin-10(11H)-one [5024-70-4]
If see Xanthone page on wiki, it says it was made from phenyl salicylate.

By a straight analog th ...
27-1-2022 at 03:05
by: Illegal Parkinson
Ketalization of Phenol
I found this also, if anybody interested:

https://de.wikipedia.org/wiki/Cyclohexadienone

http ...
6-5-2021 at 11:05
by: Illegal Parkinson
Ketalization of Phenol
I found online evidence that salicylic acid can be made to exist in the tautomeric keto form under c ...
5-5-2021 at 09:27
by: Illegal Parkinson
Ketalization of Phenol
Even supposing the whole thing is bogus, one last attempt is 1,3-Cyclohexadiene [4 + 1] Nitrene cycl ...
4-5-2021 at 10:22
by: Illegal Parkinson
Ketalization of Phenol
The benzoquinone is another interesting method.

If you form a thioketal, if the olefin tautomeriz ...
4-5-2021 at 09:32
by: Illegal Parkinson
Ketalization of Phenol

Yeah but you have 2 strong electron withdrawing groups which would disrupt the aromaticity. Come t ...
4-5-2021 at 09:09
by: Illegal Parkinson
Ketalization of Phenol
Anyway, I got to the bottom of it now anyway.

After reading Zhang & Trudell's article again: ...
4-5-2021 at 00:36
by: Illegal Parkinson
Ketalization of Phenol
E.g. Wu, Q., Hu, J., Ren, X., & Zhou, J. S. (2011). An Efficient, Overall [4+1] Cycloadditon of ...
1-5-2021 at 03:36
by: Illegal Parkinson
Ketalization of Phenol
The only problem with using Phloroglucinol as the starting material is that it is made from trinitro ...
1-5-2021 at 03:16
by: Illegal Parkinson
Preparation of Benzyl Chloride
Where do you aspire that you are going with this synthesis?

The reaction of 2 equivalents with 1 ...
28-4-2021 at 07:42
by: Illegal Parkinson
Ketalization of Phenol
In terms of the actual use for it, I have provided a direct path through to Epibatidine.

WO199906 ...
21-4-2021 at 18:18
by: Illegal Parkinson
Anisoin
https://books.google.co.uk/books?id=X_qG8wF4eMwC&pg=PA1301

According to this source, after 15 ...
21-4-2021 at 06:21
by: Illegal Parkinson
Ketalization of Phenol
Apparently, the professor is only just developing the technology very recently.

Deepankeaw, N., M ...
21-4-2021 at 00:39
by: Illegal Parkinson
Anisoin
Maybe i could tap it off with the sep funnel & try to crash it out e.g. with MeOH.

Alternativ ...
20-4-2021 at 00:02
by: Illegal Parkinson
Anisoin
I followed the procedure listed, using DMSO solvent, anisaldehyde, & NaCN, but on adding the wat ...
19-4-2021 at 23:54
by: Illegal Parkinson
Ketalization of Phenol
In the Pfizer patent, he uses an altogether different procedure to arrive at the same compound.

C ...
19-4-2021 at 23:02
by: Illegal Parkinson
Ketalization of Phenol
Based of your theory of organic chemistry,

is it possible to trap the ketal of Phenol using Dean- ...
17-4-2021 at 07:32
by: Illegal Parkinson
N-Boc-7-Azanorborn-2-one [152533-47-6]
Okay, i thought to myself if phenol-ketone can be trapped as the acetal

this concenptually might ...
27-3-2021 at 05:39
by: Illegal Parkinson
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