| Pages:
1
2 |
497
National Hazard
Posts: 778
Registered: 6-10-2007
Member Is Offline
Mood: HSbF6
|
|
Not having a 5x excess of oxidizer might help the situation.. 
About the alumina, what kind would be best? Because it looks like there are many different grades and types... Since it's just a solid suport
I wouldn't think the grade/size/porosity would be critical... Maybe you could use something like this or maybe this?
[Edited on 9-4-2009 by 497]
|
|
|
pantone159
National Hazard
Posts: 587
Registered: 27-6-2006
Location: Austin, TX, USA
Member Is Offline
Mood: desperate for shade
|
|
How do you control the extent of the oxidation? As an example, if you wanted to oxidize 1,4-butanediol to 4-hydroxybutanoic acid, with the
conventional with-solvent scheme you could add the oxidizer solution slowly to the substrate solution, assuring there is always an excess of
substrate, and with the right stoichiometry, then ensure you get mostly that desired product, with just one alcohol group oxidized. With this solid
phase method, it seems you couldn't control this, and you would get much more a mix of both, one, or no alcohol groups oxidized. (And mixes of
alcohol/aldehyde/acid.)
My personal interest would be oxidizing 1,3-propanediol to to the di-acid, so it wouldn't matter much for this, but I am curious in general.
|
|
|
Saerynide
National Hazard
Posts: 954
Registered: 17-11-2003
Location: The Void
Member Is Offline
Mood: Ionic
|
|
I wondered about that too, hence I opted for the with-solvent idea. I always figured that with so much solid oxidant, it would over oxidize for sure,
but the paper reports a 95% yield??? 
[Edit] I am still waiting on my Al2O3 to try the solvent-free method... Definately will post results when available 
[Edited on 4/19/2009 by Saerynide]
"Microsoft reserves the right at all times to monitor communications on the Service and disclose any information Microsoft deems necessary to...
satisfy any applicable law, regulation or legal process"
|
|
|
| Pages:
1
2 |
![[*]](images/xpblue/default_icon.gif){kind=icon}
