ChemRG
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The Pd/C reduction of keto to alkly
Hi，everyone!
Recently,my work is to synthesize of 1-indanecarboxylic acid.
The reaction seems very well, but I have a problem at last step.
The last step is to reduce keto to alkly, and I used Pd/C reduction.
It had been reported that the keto can be reduce to alkly successfully at 0.4Mpa and at RT.The yield is 98% for 4h.
But I monitor the reaction by TLC,there is no reactant ,and
there are two product.The Polarity of one product is stronger
than the reactant ,and another is weeker than the reactant.
Who can tell me what's the problem?
Many thanks!
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ChemRG
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The activity of 10%Pd/C(dry) is stronger than 5%Pd/C(contain 50%water)?
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not_important
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Quote: Originally posted by ChemRG  | ...
It had been reported that the keto can be reduce to alkly successfully at 0.4Mpa and at RT.The yield is 98% for 4h
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Reference? DOI?
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Nicodem
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Thread Moved
27-7-2009 at 23:01 |
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