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Author: Subject: Heterocyclic Drugs Synthesis Review
AvBaeyer
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[*] posted on 5-11-2022 at 13:40
Heterocyclic Drugs Synthesis Review


I came across this review which may be known to some of you. I found it reasonably interesting because of the broad spectrum of organic synthesis covered. Unfortunately, several of the reaction schemes contain errors. However, if you have a good eye and a reasonable knowledge of organic chemistry, they should be obvious.

Enjoy it for what is worth.

AvB

Attachment: Drugs containing nitrogen heterocycles.pdf (6.2MB)
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Dr.Bob
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[*] posted on 5-11-2022 at 17:47


Thanks for posting this, always love seeing reviews with real chemistry. And most drugs have a nitrogen in them somewhere, with a few exceptions.

Don't see much good chemistry in the current job. We seem to get mostly synthesis of stuff with poor experimentals and bad properties.
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Pumukli
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[*] posted on 8-11-2022 at 07:24


Thanks for the share!
A few interesting (long forgotten) steps here and there. :)
But: "so many possibilities and so little time"! :(
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