Broken Gears
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Venlafaxine
Hey all.
Im sorry for asking one of these stupid questions: what can I make of... But here goes.
I have change alot of things in my life recently and my life have become so much better. But all of that is another story.
My therapist and I have started decreasing my dosage of anti-depression medication, because I really dont like and need that shit anymore... I think.
I have alot of this VENLAFAXINE in high dosage laying around, because I get a smaller dose now.
So my stupid question is: Can I use it in some interesting chemistry, like making in to another Phenethylamine?
Im NOT looking for some high, Ive spend far to long of my life high.
The name of this drug is: 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexan-1-ol
Chemical formula: C17H27NO2
So there you have it. A dumb question and a little piece of my life story.
-The almost fixed Gears :-)
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Blind Angel
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Good to know that you're feeling better and that you're slowly quitting antidepressant.
To answer your question:
No, here's why:
First: To make a phenethylamine ou of it you would have to cleave the methoxy group on the phenyl and the cyclohexanol group, not easily doable (if
doable) and not economic at all
Secondly, even though they are high dosage, you'd need an enormous quantity of those pills to have a workable amount, considering lost in extraction
and in manipulation
And finaly, i wouldn't mess with pills anyways, they are full of filler that are a bugger to get rid of.
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Broken Gears
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Okay, but there must be something to do with em. I hate just to throw them down the drain, pills like that are expensives. And I dont like having them
laying around.
I could save em for awhile as a backup.
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NERV
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I hate to say it but I really doubt you'll ever be able to find a use for the pills. Just the effort needed to extract the pure
1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexan-1-ol from all of the binders and whatnot is enough of a deterrent like Blind Angel said. Plus
the only real useful compounds for organic synthesis would come from its base components, and it would be a chemist’s nightmare to try and break
that stuff down. I think your best bet is to either save 'em for a rainy day or dump ‘em down the drain.
Vir sapit qui pauca loquitur.
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Drunkguy
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hey you wanna send me the left over pills i'd like to eat them. I have read patents about O-desmethyl venla' but since venla' is already a pro drug to
this u might as well just sleep on the idea of carrying out a demethylation.
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Sandmeyer
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reading this thread is a highly recomended anti-depressant..
[Edited on 24-12-2005 by Sandmeyer]
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andresderis
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don't lose your time buddy
anphetamines are very toxic compounds...but if you want to make some interesting compund , can make something like msds or another propylamine
compunds....furthermore , make from vnlafaxine it's very hard...just forget that
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Broken Gears
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| Quote: | Originally posted by Drunkguy
hey you wanna send me the left over pills i'd like to eat them. |
You like to eat them?
It takes a week for the pills to start working right. Besides if you are not taking in on a daily basic as a tretment, you'll get a Serotonin syndrome
(overdose of some kind)
I know we a not allowed to trade or sell on this site, but I have no use for them.
Thank you all for taking you time to answer my question and enlighting a little chemistry for me.
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stygian
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I have used effexor recreationally before. A single time use dose (high enough, 150mg+) creates a pretty intense euphoria. That whole "takes a week
or two" business is BS. The hangover is pretty awful though.
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Broken Gears
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As if as I know its "depot" pills and that means that the active drug is slowly released into your system. Making the effeckt longer throughout the
day, not creating short rush/high. I have never heard of abuse of these pills, but then again I may be wrong.
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Drunkguy
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I wouldn't really say the effects are 'recreational'. Infact by saying I would eat the pills was simply stating that they are better than nothing,
this is not saying that they are fun. They are what is known as a 'dual reuptake inhibitor' meaning that in addition to serotonin (boring), they also
inhibit the uptake or norephedrine. Stimulant drugs such as amphetamine also inhibit the uptake of norephedrine. Repeated administration of
venlafaxine over several weeks/months leads to a down regulation of beta-adrenergic receptors. This means if you continue taking it for any length of
time you'll be left with a typical serotonin reuptake inhibitor.
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andresderis
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norephedrine= dopamine'???
if it doesn't something like that , you're very wrong
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stygian
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Norephedrine isn't correct. It's norepinephrine (noradrenaline). It's norephedrine with catechol instead of mere phenyl ring. Serotonin isn't
boring. I would take around 300mg at a time and have a geeky smile plastered on my face all day. Not boring. The NE depletion the next day, as i
said, is pretty awful.
Edit: I also remember reading somewhere that very high doses of venlafaxine are also Dopamine reuptake inhibitors (very strange pharmacology
venlafaxine has, different actions at different dosages)
[Edited on 27-12-2005 by stygian]
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