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Author: Subject: Ridiculously easy alkali organometallic synth? (Benzyllithium)
forgottenpassword
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[*] posted on 2-12-2014 at 12:15


Quote: Originally posted by chemrox  
Quote: Originally posted by forgottenpassword  
I could find the paper if there is a specific interest.

Please do find the paper and post it here or in refs "for chemrox"
I don't know what you mean by specific need but I'm looking for ways to make a cmpd with an aryl group attached under conditions that a Li reagent would be helpful.


The Gaylord Chemical review (110B) is where I first picked it up: The paragraph on page 4 under "Dimsyl Sodium Solutions with Other Bases".

It mentions the reference (85) to Hunter and Cram (ja00976a018) using KOH, as well as the two papers using KOtBu by Russell and Becker (ja00904a024) and Russell and Mikol (ja00975a025), references 83 and 84 respectively. The reference for the use of other alkoxides (82) is from some obscure company report which I couldn't find, but they suggest in that paragraph that they can be used similarly to KOtBu.

The Russell and Mikol paper is a good one to start with as it makes the chemistry plain.

Attachment: 110B.pdf (1.1MB)
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Attachment: ja00976a018.pdf (328kB)
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Attachment: ja00975a025.pdf (236kB)
This file has been downloaded 413 times

Attachment: ja00904a024.pdf (197kB)
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[Edited on 2-12-2014 by forgottenpassword]
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