Charlie80
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NRX-1074
I'm looking to identify a compound called nrx-1074. Also looking to find synthesis pathway.
It may be hidden here:
https://www.google.com/patents/WO2010033757A1?cl=en&dq=n...
Any leads welcome. There may be compensation for those who strike gold.
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Loptr
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It sounds like the company hasn't released any more details on the compound. NRX-1074 might be a public release codename so that it can't be matched
up to any patents easily. It probably has already been patented and easily available if you read the patents, but they aren't going to tell you which
one it is.
I also found there is a lot of freakin' interest in this compound just by a quick google search. It looks like it might be similar to ketamine, except
with nootropic function? The longecity forum has several threads about it.
EDIT: Patent WO2014120783 A1 mentions NRX-1076, so it might be close to that timeframe of being published. Filed Jan 2014, and published Aug 2014.
[Edited on 28-4-2015 by Loptr]
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IrC
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Do not understand why someone would be searching for the synthesis of something they know nothing about. Are we not wishing to state what it is we
know thus requiring subterfuge?
http://www.freepatentsonline.com/result.html?sort=relevance&...
I imagine it is obvious anyone finding gold is rewarded with... gold.
"Science is the belief in the ignorance of the experts" Richard Feynman
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Loptr
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I just figured I would find it and then force them to pay before handing it over. 
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IrC
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Good idea. I was posting to the OP when I concluded it appears they for some reason are not really saying what they knew about the 'mysterious
compound'.
http://en.wikipedia.org/wiki/NRX-1074
"Science is the belief in the ignorance of the experts" Richard Feynman
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Loptr
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Right now I think I know as much about NRX-1074 as anyone outside the company. I have found related work that isn't owned by Naurex Inc. that might be
related to NRX-1074, which is from a previous institution.
In other news, it seems that GLYX-13 has had its patent extended to 2030. Good for them.
Not to mention that NRX-1074 seems to be an oral formulation of their GLYX-13 (intravenous) product. 
[Edited on 28-4-2015 by Loptr]
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redan-yadayada
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The structure of this compound has been disclosed in this paper. Could anyone help me with a synthesis route for the unusual intermediates?
Thank you.
[Edited on 22-9-2015 by redan-yadayada]
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aga
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Yes.
No idea who they are, but there are people that could help.
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Dan Vizine
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redan-yadayada,
Seeing as the paper is 203 pages long, and I have more ambition than time, would you please indicate which page the structure is on?
[Edited on 2-10-2015 by Dan Vizine]
"All Your Children Are Poor Unfortunate Victims of Lies You Believe, a Plague Upon Your Ignorance that Keeps the Youth from the Truth They
Deserve"...F. Zappa
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deltaH
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| Quote: | NRX-1074 (threonyl-prolyl-2R-(2-benzyl)-prolyl-threonine amide) has
the same tetrapeptide sequence as rapastinel (GLYX-13) except that the second Pro is
benzylated. |
Supporting info:
[Edited on 2-10-2015 by deltaH]
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Dan Vizine
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Good luck in your search. Maybe someone will have access to the synthetic papers referenced in your link.
"All Your Children Are Poor Unfortunate Victims of Lies You Believe, a Plague Upon Your Ignorance that Keeps the Youth from the Truth They
Deserve"...F. Zappa
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