Melgar
Anti-Spam Agent
Posts: 2004
Registered: 23-2-2010
Location: Connecticut
Member Is Offline
Mood: Estrified
|
|
Halide-free Friedel-Crafts acylation, using P2O5 as both Lewis acid and acid dehydrator
By supporting phosphorus pentoxide on silica gel, because otherwise it turns into a sticky mess and stops reacting, researchers were able to perform
Friedel-Crafts acylation starting with the organic acids (rather than acid halides or acid anhydrides) and the aromatic substrate. This would result
in superior yields to ordinary Friedel-Crafts with an acid anhydride, since the anhydride reforms after it reacts. Paper is attached.
Attachment: p2o5-friedel-crafts.pdf (313kB) This file has been downloaded 440 times
[Edited on 10/24/16 by Melgar]
|
|
myristicinaldehyde
Hazard to Others
Posts: 166
Registered: 23-4-2016
Location: .͐͌ ͛҉̻̫̰̻̖E̮ͮ̐́̚ ̢̗̅̉ͩ͂̒̌.̯̻̺̯̀̎͂̄ͩ̚
Member Is Offline
Mood: сорок пять
|
|
Chemplayer has a video on this too-https://www.youtube.com/watch?v=xAUlglOiVos
|
|