Difference between revisions of "Isopropyl nitrite"
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| − | Isopropyl nitrite is a highly flammable organic ester. | + | '''Isopropyl nitrite''' is a highly flammable organic ester. |
==Properties== | ==Properties== | ||
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==Preparation== | ==Preparation== | ||
| − | Concentrated [[Hydrochloric acid|hydrochloric acid]] is slowly dripped onto [[sodium nitrite]] suspended in [[isopropanol]] , generating [[nitrous acid]] which reacts with the alcohol. The concentration of isopropanol should be less than 100% to ensure the solution does not get too acidic (which will rapidly decompose the ester) and that some of the precipitate byproducts dissolve. Diluted [[sulfuric acid ]] can also be used but this will result in a larger amount of precipitate due to [[ | + | Concentrated [[Hydrochloric acid|hydrochloric acid]] is slowly dripped onto [[sodium nitrite]] suspended in [[isopropanol]] , generating [[nitrous acid]] which reacts with the alcohol. The concentration of isopropanol should be less than 100% to ensure the solution does not get too acidic (which will rapidly decompose the ester) and that some of the precipitate byproducts dissolve. Diluted [[sulfuric acid]] can also be used but this will result in a larger amount of precipitate due to [[sodium sulfate]]'s lower solubility compared to [[sodium chloride]] . |
Every reagent should be as cold as possible to limit decomposition to nitrogen oxides. An icebath may be needed. | Every reagent should be as cold as possible to limit decomposition to nitrogen oxides. An icebath may be needed. | ||
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==Handling== | ==Handling== | ||
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===Safety=== | ===Safety=== | ||
As well as being highly flammable, being an organic nitrite it promotes vascodilation in the body, pushing more blood to the brain. Hence breathing fumes of isopropyl nitrite can have some mild strange side effects that mostly end up in a headache. Proper ventaliation is required when using this compound. | As well as being highly flammable, being an organic nitrite it promotes vascodilation in the body, pushing more blood to the brain. Hence breathing fumes of isopropyl nitrite can have some mild strange side effects that mostly end up in a headache. Proper ventaliation is required when using this compound. | ||
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===Storage=== | ===Storage=== | ||
| − | Storage is best done in a cold place such as a fridge or freezer, but care must be taken to | + | Storage is best done in a cold place such as a fridge or freezer, but care must be taken to prevent as the vapors travel quickly and can easily find a source of ignition. |
If care is taken to make sure the ester does not contain any acid before storage, it will not quickly decompose and may be stored cold for many months. | If care is taken to make sure the ester does not contain any acid before storage, it will not quickly decompose and may be stored cold for many months. | ||
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| − | Acid hydrolysis of the compound destroys it quickly, with the evolution of nitrogen oxides. It is | + | ===Disposal=== |
| + | Acid hydrolysis of the compound destroys it quickly, with the evolution of nitrogen oxides. It is recommeded to either burn it or simply let it evaporate over pouring it down a sink, as its solvent properties may adversely affect a plumbing system. | ||
==References== | ==References== | ||
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===Relevant Sciencemadness threads=== | ===Relevant Sciencemadness threads=== | ||
| + | [[Category:Chemical compounds]] | ||
| + | [[Category:Organic compounds]] | ||
| + | [[Category:Nitrites]] | ||
[[Category:Esters of inorganic acids]] | [[Category:Esters of inorganic acids]] | ||
[[Category:Psychoactive substances]] | [[Category:Psychoactive substances]] | ||
Revision as of 12:53, 9 August 2015
Isopropyl nitrite is a highly flammable organic ester.
Contents
Properties
Chemical
Isopropyl nitrite reacts with hydrazine hydrate and sodium hydroxide to form sodium azide .
Physical
Isopropyl nitrite is straw yellow colour and has a sweet, not-unpleasant smell. It is immiscible and less dense than water. Isopropyl nitrite has a very high vapour pressure and a low boiling point, although it will decompose on boiling to produce nitrogen oxides and isopropanol . A low flash point combined with the high vapour pressure means it is very easy to ignite.
Availability
Isopropyl nitrite is better made in a home lab setting.
Preparation
Concentrated hydrochloric acid is slowly dripped onto sodium nitrite suspended in isopropanol , generating nitrous acid which reacts with the alcohol. The concentration of isopropanol should be less than 100% to ensure the solution does not get too acidic (which will rapidly decompose the ester) and that some of the precipitate byproducts dissolve. Diluted sulfuric acid can also be used but this will result in a larger amount of precipitate due to sodium sulfate's lower solubility compared to sodium chloride .
Every reagent should be as cold as possible to limit decomposition to nitrogen oxides. An icebath may be needed.
Projects
- Make sodium azide
- Antidote for hydrogen sulfide and cyanide poisonings
Handling
Safety
As well as being highly flammable, being an organic nitrite it promotes vascodilation in the body, pushing more blood to the brain. Hence breathing fumes of isopropyl nitrite can have some mild strange side effects that mostly end up in a headache. Proper ventaliation is required when using this compound.
In case of nitrite poisoning, small dosages of methylene blue are recommended (0.1 ml of 1% solution per kilogram of patient's weight, intravenously). Not to be confused with large dosages, which are toxic in the same way nitrites are, and are used to treat poisoning with blood agents like cyanides, carbon monoxide and hydrogen sulfide (isopropyl nitrite itself can work as an antidote in these cases).
Storage
Storage is best done in a cold place such as a fridge or freezer, but care must be taken to prevent as the vapors travel quickly and can easily find a source of ignition.
If care is taken to make sure the ester does not contain any acid before storage, it will not quickly decompose and may be stored cold for many months.
Disposal
Acid hydrolysis of the compound destroys it quickly, with the evolution of nitrogen oxides. It is recommeded to either burn it or simply let it evaporate over pouring it down a sink, as its solvent properties may adversely affect a plumbing system.
