| IUPAC name
| Preferred IUPAC name
| Other names
|Molar mass||76.12 g/mol|
|Appearance||White crystalline solid|
|Melting point||182 °C (360 °F; 455 K)|
| 13.7 g/100 ml (25 °C)|
14.2 g/100 ml (25 °C)
|Solubility|| Reacts with acids|
Soluble in ethanol, methanol
Almost insoluble in diethyl ether, hexane
|Solubility in ethanol|| 3.6 g/100 ml (20 °C)|
4.7 g/100 ml (31.9 °C)
6.3 g/100 ml (45 °C)
8.5 g/100 ml (58 °C)
9.8 g/100 ml (64.7 °C)
|Solubility in methanol|| 11.9 g/100 ml (25 °C)|
16.4 g/100 ml (40.7 °C)
22 g/100 ml (53.7 °C)
24.6g/100 ml (61.9 °C)
|Safety data sheet||Sigma-Aldrich|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|1,750 mg/kg (rat, oral)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Thiourea is an organosulfur compound with the formula SC(NH2)2. It is structurally similar to urea, except that the oxygen atom is replaced by a sulfur atom, thus the properties of urea and thiourea differ significantly.
Oxidation of thiourea with hydrogen peroxide produces thiourea dioxide
Thiourea is a colorless white solid, soluble in water. It is odorless and has a taste, often described as bitter. It sublimes under vacuum between 150-160 °C.
Thiourea is sold by many lab and chemical suppliers.
The liquid silver cleaning product TarnX contains thiourea, a detergent and sulfamic acid.
Thiourea can be easily produced from ammonium thiocyanate via heat treatment at 180 °C.
Industrially it is produced by the reaction of hydrogen sulfide with calcium cyanamide in the presence of carbon dioxide.
- Make thiourea peroxide
- Silver polishing
- Preparation of pharmaceuticals
- Auxiliary agent in diazo paper
- Reducing peroxides to the corresponding diols
- Converting alkyl halides to thiols
Thiourea displays average toxicity. The LD50 values given in literature are between 125 and 1,750 mg/kg for rats (oral dose).
A goitrogenic effect (enlargement of the thyroid gland) has been reported for chronic exposure, reflecting the ability of thiourea to interfere with iodide uptake.
In closed plastic bottles.
Thiourea can be neutralized with a strong oxidizing solution.