Difference between revisions of "Inositol"

From Sciencemadness Wiki
Jump to: navigation, search
 
Line 7: Line 7:
 
| OtherNames = cis-1,2,3,5-trans-4,6-Cyclohexanehexol<br>Cyclohexanehexol<br>Mouse antialopecia factor<br>Nucite<br>Phaseomannite<br>Phaseomannitol
 
| OtherNames = cis-1,2,3,5-trans-4,6-Cyclohexanehexol<br>Cyclohexanehexol<br>Mouse antialopecia factor<br>Nucite<br>Phaseomannite<br>Phaseomannitol
 
<!-- Images -->
 
<!-- Images -->
| ImageFile =  
+
| ImageFile = Myo_Inositol.jpg
| ImageSize =  
+
| ImageSize = 270px
 
| ImageAlt =  
 
| ImageAlt =  
 
| ImageName =  
 
| ImageName =  
Line 64: Line 64:
 
| pKa =  
 
| pKa =  
 
| pKb =  
 
| pKb =  
| Solubility = 14 g/100 ml (25 ºC)
+
| Solubility = 14 g/100 ml (25 ºC), <br/> 28 g/100 mL (60 °C)<ref>W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition),
| SolubleOther = Moderate soluble in [[methanol]]<br>Slightly soluble in [[Dimethyl sulfoxide|DMSO]]<br>Insoluble in alcohols, [[dichloromethane]], [[dimethylformamide]], [[tetrahydrofuran]]<ref>https://www.researchgate.net/post/Does_anyone_know_about_solubility_of_Inositol_except_for_water</ref>
+
Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 693</ref>
 +
| SolubleOther = Moderate soluble in [[methanol]]<br>Slightly soluble in [[Dimethyl sulfoxide|DMSO]], [[ethanol]]<br>Insoluble in alcohols, [[dichloromethane]], [[dimethylformamide]], [[tetrahydrofuran]]<ref>https://www.researchgate.net/post/Does_anyone_know_about_solubility_of_Inositol_except_for_water</ref>, [[diethyl ether]]<ref>W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition),
 +
Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 693</ref>
 
| Solvent =  
 
| Solvent =  
 
| VaporPressure = ~0 mmHg
 
| VaporPressure = ~0 mmHg
Line 115: Line 117:
  
 
Oxidation with nitric acid gives rhodizonic acid.
 
Oxidation with nitric acid gives rhodizonic acid.
 +
 +
Inositol may be recrystallized from water or 50% ethanol/water, from which a dihydrate results. It may be dehydrated to a non-hygroscopic anhydrous form.<ref>W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition),
 +
Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 692</ref>
  
 
===Physical===
 
===Physical===
Line 120: Line 125:
  
 
==Availability==
 
==Availability==
Inositol is available in many health food stores.
+
Inositol is available in many health food stores. It is sold as a food supplement, sometimes mixed with taurine.
  
 
It can also be bought online cheaply.
 
It can also be bought online cheaply.

Latest revision as of 21:41, 27 February 2021

Inositol
Myo Inositol.jpg
Names
IUPAC name
(1R,2R,3S,4S,5R,6S)-cyclohexane-1,2,3,4,5,6-hexol
Other names
cis-1,2,3,5-trans-4,6-Cyclohexanehexol
Cyclohexanehexol
Mouse antialopecia factor
Nucite
Phaseomannite
Phaseomannitol
Properties
C6H12O6
Molar mass 180.16 g/mol
Appearance White solid
Odor Odorless
Density 1.752 g/cm3
Melting point 225–227 °C (437–441 °F; 498–500 K)
Boiling point Decomposes
14 g/100 ml (25 ºC),
28 g/100 mL (60 °C)[1]
Solubility Moderate soluble in methanol
Slightly soluble in DMSO, ethanol
Insoluble in alcohols, dichloromethane, dimethylformamide, tetrahydrofuran[2], diethyl ether[3]
Vapor pressure ~0 mmHg
Hazards
Safety data sheet Sigma-Aldrich (myo-inositol)
Flash point 143 °C
Lethal dose or concentration (LD, LC):
10,000 mg/kg (mouse, oral)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound with formula C6H12O6, a sugar alcohol. It exists in nine possible stereoisomers, of which the most prominent form, widely occurring in nature, is cis-1,2,3,5-trans-4,6-cyclohexanehexol, or myo-inositol (former names meso-inositol or i-inositol). Its taste has been assayed at half the sweetness of table sugar (sucrose).

Properties

Chemical

Inositol can be nitrated to give inositol hexanitrate using a nitrating mixture.

Oxidation with nitric acid gives rhodizonic acid.

Inositol may be recrystallized from water or 50% ethanol/water, from which a dihydrate results. It may be dehydrated to a non-hygroscopic anhydrous form.[4]

Physical

Inositol is a crystalline solid, soluble in water.

Availability

Inositol is available in many health food stores. It is sold as a food supplement, sometimes mixed with taurine.

It can also be bought online cheaply.

Preparation

Inositol is best bought than made.

Projects

Handling

Safety

Inositol has low toxicity and it's 100% edible. Lab-grade inositol however, isn't.

Storage

Inositol should be kept in closed bottles, plastic bottles are sufficient.

Disposal

Inositol doesn't require special disposal. Discard it as you wish.

References

  1. W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition), Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 693
  2. https://www.researchgate.net/post/Does_anyone_know_about_solubility_of_Inositol_except_for_water
  3. W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition), Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 693
  4. W.L.F. Armarego, C.L.L. Chai, Purification of Laboratory Chemicals (Sixth Edition), Butterworth-Heinemann, 2009, ISBN 9781856175678, p. 692

Relevant Sciencemadness threads