| IUPAC names
| Other names
|Molar mass||88.11 g/mol|
|Melting point||11.8 °C (53.2 °F; 284.9 K)|
|Boiling point||101.1 °C (214.0 °F; 374.2 K)|
|Solubility||Miscible with most organic solvents|
|Vapor pressure||29 mmHg (20 °C)|
Std enthalpy of
|Safety data sheet||Sigma-Aldrich|
|Flash point||12 °C (54 °F; 285 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
| 5.7 g/kg (mouse, oral)|
5.2 g/kg (rat, oral)
3.9 g/kg (guinea pig, oral)
7.6 g/kg (rabbit, dermal)
LC50 (Median concentration)
| 10,109 ppm (mouse, 2 hr)|
12,568 ppm (rat, 2 hr)
| Ethylene oxide|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
1,4-Dioxane, also known as diethylene ether, diethylene dioxide or simply dioxane, as the 1,2 and 1,3 isomers are rarely encountered, is a heterocyclic organic compound, a cyclic ether.
Dioxane can be reacted with dry chlorine gas to yield trans-2,3-dichloro-1,4-dioxane.
Dioxane is a colorless liquid, with a faint sweet odor similar to that of diethyl ether. It is miscible with many solvents and is hygroscopic. Dioxane boils at 101.1 °C and freezes at 11.8 °C.
Dioxan can be bought from eBay.
Dioxane is produced by the acid-catalysed dehydration of ethylene glycol, using conc. sulfuric acid as catalyst. The reaction takes place under reflux. Commercial anti-freeze can be safely used as EG source, regardless of impurities and additives, though concentrated anti-freeze gives a better yield than the diluted version.
Frogfot wrote a synthesis of dioxane.
- Stabilize trichloroethane
- Medium for organic reactions
- Purification of metallic sodium
Dioxane is considered carcinogenic. It is also very flammable.
Dioxane is sometimes confused with dioxin.
Dioxane should be stored in closed bottles, with a reducing agent to prevent the formation of peroxides. Dioxane is safe to keep without anti-oxidants for maximum one year, after which the levels of peroxides become too dangerous to handle.
Dioxane can be safely burned, if there are no peroxides. If the dioxane tests positive for peroxides, neutralize peroxides first. Reducing agents, like as ferrous sulfate, sodium bisulfite or metabisulfite added in excess can be used to neutralize the peroxides. After incineration, the ether should be tested again for peroxides and if none are present, it can be safely burned. If it's an old bottle, which has peroxides on the cap, do not open the bottle, instead take it to a remote of special area and safely detonate it. The latter may or require professional help.