Glycine on a watch glass
| IUPAC name
| Preferred IUPAC name
| Other names
|Molar mass||75.07 g/mol|
|Melting point||233–240 °C (451–464 °F; 506–513 K) (decomposition)|
| 24.99 g/100 ml (25 °C)|
39.1 g/100 ml (50 °C)
54.4 g/100 ml (75 °C)
67.2 g/100 ml (100 °C)
|Solubility|| Soluble in pyridine|
Sparingly soluble in acetone, ethanol
Insoluble in diethyl ether, hydrocarbons
|Solubility in ethanol||0.06 g/100 g|
|Vapor pressure||~0 mmHg|
|Acidity (pKa)|| 2.34 (carboxyl)|
|Safety data sheet||Sigma-Aldrich|
|Flash point||176.67 °C|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|2,600 mg/kg (mouse, oral)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Glycine (symbol Gly or G) is the simplest amino acid, which has a single hydrogen atom as its side chain, having the formula NH2-CH2-COOH. It is one of the proteinogenic amino acids.
Glycine is the only achiral proteinogenic amino acid.
In aqueous solution, glycine itself is amphoteric: at low pH the molecule can be protonated with a pKa of about 2.4 and at high pH it loses a proton with a pKa of about 9.6 and can therefore form salts both with acids and bases.
Glycine is an odorless while solid, soluble in water, with a sweet taste.
Glycine is sold by chemical suppliers. It can also be bought online.
Preparation of glycine unnecessary, as it is too cheap to make it yourself from precursors.
- Grow bacterial cultures
- Buffering agent
Glycine has low toxicity.
Glycine is best kept in closed bottles, away from moisture.
No special disposal is required. Discard it as you wish.
- Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 765