| IUPAC name
| Other names
|Molar mass||185.948 g/mol|
|Appearance||Whiteish crystalline solid|
|Melting point||81 °C (178 °F; 354 K)|
|Boiling point||208 °C (406 °F; 481 K) (decomposes)|
|60 g/100 ml (20 ºC)|
|Solubility|| Soluble in diethyl ether, ethanol, methanol|
Slightly soluble in chloroform
|Vapor pressure||6.42 mmHg|
|Safety data sheet||Sigma-Aldrich|
| Acetic acid|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Iodoacetic acid or monoiodoacetic acid is a derivative of acetic acid, an organoiodine compound.
Iodoacetic acid is a powerful alkylating agent.
Iodoacetic acid is a white or yellowish crystalline solid, very soluble in water and organic solvents.
Due to its hazards, iodoacetic acid is hard to acquire.
- Cl-CH2COOH + KI → I-CH2COOH + KCl
- Alkylating agent
Iodoacetic acid is corrosive and highly poisonous. As the toxicity of monohaloacetic acids increases with halogen size, iodoacetic acid is more toxic than bromoacetic acid and much more toxic than chloroacetic acid.
Iodoacetic acid should be kept in closed bottles. It's recommended to be stored below 0 °C, in a special freezer, to limit sublimation or decomposition.
Adding an excess of sodium hydroxide will convert it to the non-toxic sodium glycolate/glycolic acid.