Low purity forerun (left) and high purity end run (right) tert-amyl alcohol, obtained via Grignard reaction route.
| IUPAC name
| Other names
|Molar mass||88.15 g/mol|
|Density||0.8096 g/cm3 (20 °C)|
|Melting point||−9 °C (16 °F; 264 K)|
|Boiling point||102.4 °C (216.3 °F; 375.5 K)|
|12 g/100 ml|
|Solubility||Miscible with acetone, diethyl ether, benzene, chloroform, ethanol, glycerol, oils|
|Vapor pressure||1.6 kPa (at 20 °C)|
Std enthalpy of
|Safety data sheet||Sigma-Aldrich|
|Flash point||19 °C (66 °F; 292 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|1,000 mg/kg (rat, oral)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
tert-Amyl alcohol, like all tertiary alcohols, is not readily oxidized. Due to the high stability of the tert-amyl cation, it is quite easy to prepare tert-amyl halides by reaction of the alcohol with the corresponding hydrogen halide at room temperature.
tert-Amyl alcohol is a colorless liquid with a camphor-like odor, often described as unpleasant. It is somewhat soluble in water, but miscible with other organic solvents, like alcohols and halocarbons.
tert-Pentanol is sold by chemical suppliers. Can also be bought online.
Can also be extracted via fractional distillation from fusel oil, though you will need large amounts of it.
tert-Amyl alcohol can be prepared via the bromoethylethylmagnesium Grignard with acetone route.
NurdRage has a good video on this process.
tert-Amyl alcohol is flammable and a skin irritant, though it's not very flammable in cold environment.
Ingestion or inhalation produces intoxication similar in many ways to ethanol, though it is around 20 times more potent by volume and produces longer-lasting effects. Exposure to vapor in the lab or accidental ingestion may cause temporary loss of physical and mental faculties or even sedation.
tert-Amyl alcohol should be kept in closed bottles made of glass or chemically resistant plastic such as HDPE, preferably in a flammables cabinet.
Can be safely burned outside. Combustion products are not harmful.