Methyl formate

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Methyl formate
Methyl formate freshly distilled in RBF.jpg
Freshly distilled pure methyl formate, made from 85% formic acid and methanol.
Methyl formate structure.png
Chemical structure
IUPAC name
Methyl formate
Preferred IUPAC name
Methyl formate
Other names
Molar mass 60.05 g/mol
Appearance Colorless volatile liquid
Odor Fruity, lemonade-like
Density 0.987 g/cm3 (15 °C)
0.98 g/cm3 (20 °C)
Melting point −100 °C (−148 °F; 173 K)
Boiling point 31–32 °C (88–90 °F; 304–305 K)
30 g/100 ml (20 °C)
23 g/100 ml (25 °C)
Solubility Miscible with glacial acetic acid, acetone, chloroform, ethanol, methanol
Vapor pressure 476 mmHg (20 °C)
Safety data sheet Simga-Aldrich
Flash point −19 °C
Lethal dose or concentration (LD, LC):
1,500 mg/kg (rat, oral)
1,622 mg/kg (rabbit, oral)
Related compounds
Related compounds
Ethyl formate
Methyl acetate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Methyl formate or methyl methanoate, is the methyl ester of formic acid, the simplest ester.



Methyl formate can be hydrolyzed to methanol and formic acid using a strong acid.

Aminolysis of methyl formate gives formamide or dimethylformamide.

Like its precursor, methanol, methyl formate burns with a nearly invisible flame.


Methyl formate is a colorless organic liquid, with an ethereal odor, low surface tension and high vapor pressure. It has a melting point of −100 °C and boils at 32 °C. Methyl formate has a density of 0.97 g/cm3 at standard conditions. It is soluble in water (30 g/100 ml) and other solvents, such as acetone, diethyl ether, ethanol, ethyl acetate. The flash point of methyl formate is -19 °C and its auto-ignition temperature is 449 °C.


Methyl formate is available from chemical suppliers.


Methyl formate can be synthesized by reacting anhydrous formic acid with dry methanol, over a strong desiccant, such as calcium chloride. The addition of calcium chloride isn't necessary, but it helps to limit the amount of water being pushed in the condenser by the boiling methyl formate vapors and can also act as boiling chips, which is very important, as due to its low boiling point, methyl formate may bump if the heating element heats the flask too much, unless you have very good temperature control. The resulting distillate is purified by salting out the water and methanol impurities with anh. calcium chloride, followed by drying with anhydrous MgSO4. Due to its low boiling point, methyl formate can be easily purified via fractional distillation.

Industrially, it is prepared by via carbonylation of methanol, using sodium methoxide as a catalyst and pyridine as a temperature promoter, in an extremely dry medium. The smallest traces of water can disrupt the reaction.


This route however is uneconomical for the amateur chemist, thus the first method is cheaper and more accessible.




Methyl formate vapors may irritate lungs, so it's best to work in a well ventilated area. Since its boiling point is lower than the human body temperature, samples of methyl formate should not be kept too long in hand.


Due to its low boiling point, methyl formate should be stored in closed bottles, away from any source of heat or light, preferable in a fridge. This is mandatory during hot summers.


Methyl formate can be safely burned.



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