Methyl isobutyl ketone
| IUPAC name
| Other names
2-Methylpropyl methyl ketone
Isobutyl methyl ketone
|Molar mass||100.16 g/mol|
|Density||0.802 g/cm3 (20 °C)|
|Melting point||−84.7 °C (−120.5 °F; 188.5 K)|
|Boiling point||117–118 °C (243–244 °F; 390–391 K)|
|1.91 g/100 ml (20 °C)|
|Solubility||Miscible with acetone, benzene, chloroform, diethyl ether, ethanol|
|Vapor pressure||16 mmHg (20 °C)|
|Safety data sheet||Sigma-Aldrich|
|Flash point||14 °C (57 °F; 287 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|2.080 mg/kg (rat, oral)|
|Methyl ethyl ketone|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Methyl isobutyl ketone (MIBK) is the organic compound with the formula (CH3)2CHCH2C(O)CH3.
Methyl isobutyl ketone is flammable and will burn if ignited in open air, releasing carbon dioxide, water vapors and soot.
Reductive coupling of MIBK with 4-aminodiphenylamine yields N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylene diamine (6PPD), an antiozonant used in tires.
MIBK is a colorless liquid, with a pleasant odor similar to that of other ketones, which is flammable and somewhat volatile.
MIBK is sold by chemical suppliers.
In US, it is classified as DEA list II chemical, due to its use as substitute ketone in the processing of cocaine. Other countries may have similar restrictions.
Methyl isobutyl ketone is made from acetone via a three-step process. Firstly acetone undergoes an aldol reaction to give diacetone alcohol, which readily dehydrates to give mesityl oxide. Mesityl oxide can then be hydrogenated to give MIBK.
- Liquid-liquid extractions
- Solvent for nitrocellulose, lacquers, polymers, resins
- Make 6PPD, an antiozonant used in tires
MIBK is irritant and flammable.
Should be kept in closed bottles.
Can be safely burned outside or in an incinerator.