Freshly prepared methyl iodide, stored over copper
| IUPAC name
| Other names
|Molar mass||141.94 g/mol|
|Appearance|| Colorless liquid|
Brownish liquid (old sample)
|Density||2.28 g/cm3 (at 20 °C)|
|Melting point||−66.5 °C (−87.7 °F; 206.7 K)|
|Boiling point||42.5 °C (108.5 °F; 315.6 K)|
|1.4 g/100 ml (at 20 °C)|
|Solubility||Miscible with acetone, alcohols, carbon tetrachloride, chloroform, diethyl ether|
|Vapor pressure||54.4 kPa (at 20 °C)|
Std enthalpy of
|Safety data sheet||ScienceLab|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
| 76 mg/kg (oral, rat)|
800 mg/kg (dermal, guinea pig)
LC50 (Median concentration)
| 1550 ppm (rat, 30 min)|
860 ppm (mouse, 57 min)
220 ppm (rat, 4 hr)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Methyl iodide or iodomethane is an organic chemical compound, which appears as a dense liquid, insoluble in water, mainly used as a methylating agent. It has the chemical formula CH3I, sometimes written as MeI.
Methyl iodide will hydrolyze in the presence of an alkali to methanol and iodide:
- CH3I + MOH → CH3OH + MI
Methyl iodide is a dense, colorless (though old samples have a brownish color) liquid, immiscible in water, but miscible with many solvents such as diethyl ether, ethanol, methanol and soluble in acetone and carbon tetrachloride. Methyl iodide has a strong and pungent ether-like odor.
Methyl iodide is sold by various chemical suppliers, though it's difficult to acquire. It can sometimes be found on eBay.
Methyl iodide used to be available as a pesticide up until 2012, when it was removed due to its carcinogenic effects.
- Make esters
- Make toluene
Iodomethane is toxic and carcinogenic.
Methyl iodide MUST be kept away from heavy metals, such as mercury, lead, cadmium, arsenic or thallium, as this will generate extremely toxic heavy methyl iodides, which are more toxic than their corresponding metals. It's ABSOLUTELY CRUCIAL to avoid contact with mercury amalgam, as this will yield the volatile compound dimethylmercury, one of the most deadly contact poisons known, second only to nerve agents, which readily penetrates butyl, latex, neoprene and PVC protective equipment.
Methyl iodide must be stored in amber bottles, in dark well ventilated places, away from light. Copper or silver wire can be added as a stabilizer.
Methyl iodide can be hydrolyzed to methanol with sodium hydroxide.